1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the therapy of several myeloma. Its synthesis or study is crucial for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound while in the synthesis of imatinib, a drug that targets particular types of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is vital for optimizing the production course of action and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is applied to deal with breast most cancers, and these intermediates are involved with its generation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the remedy of breast most cancers. Many intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate 3-d]pyrimodin-5-yl)ethyl]benzoic acid is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers including ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is associated with the synthesis of adamantane derivatives, which have many applications, including antiviral Homes.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, an oral drug for sort two diabetic issues that inhibits the enzyme DPP-four to regulate blood sugar stages.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, which can be used in Bortezomib intermediate foods, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication used to control form two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).